What is the difference between IRMA and Neovascularization – NVE: Example One

If your thinking what the heck is the difference between IRMA (intraretianl microvascular abnormalities) and NVD (neovascularization of the disk), or NVE (neovascularization everywhere else) you are not alone. For help distinguishing between them:

• Usually the IRMA is within the retina and does not occur on the disk.
• It is much more discrete, darker in color with less defined borders typically does not leak
• IRMA vessels may be few in number that are curly and do not look “logical” or going to any particular place
• Neovascularization is on top or even growing into the vitreous and are associated with leaks and bleeding.
• Neovascularization is usually seen after IRMA and could be described as a more “sick” looking eye.

Sources: Optholomology by Brian Bucca, OD, FAAO, Chief of EyeCare UC Denver and Intraretinal Microvascular Abnormality (IRMA) Chris Kirkpatrick, MD